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  • An article published on The American Journal on Addictions stated that women that are pregnant who were enslaved by opioids were strongly enthusiastic about antagonist treatment, especially the one that involves the use of naltrexone to combat their alcohol abuse disorder. Using two separate drugs to shed pounds can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you should err to the side of caution and let the FDA do its job and demand some study be done in order that the public recognizes the side effects and risks of the medications before we drive them. Keep in mind that drug companies will be in business to earn money and that they would say everything to keep people on his or her medications. Researchers found out that participants using this drug for a year, dropped excess weight within a month and have kept the weight off through the entire 56 weeks with the study. Contrave is really a combination from the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which are made up of several active ingredient, which might make them far better and safer. Combo-pilling may be the newest fad or in addition to this the newest into the future under scrutiny and therefore it is just more publicly known lately, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills has become popular will be the fact that by right now there are not any long term prescription diet pills that have been authorized by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be authorized by the FDA. Seizures really are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug could also raise blood pressure level and heartrate, and shouldn't be used in individuals with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure level and heartbeat and must not used in patients with uncontrolled high hypertension, as well as by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients with a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients to the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking. Acamprosate also functions eliminate the desire to drink through the elimination of the the cravings for having a drink. The major difference between Naltrexone and Acamprosate is Acamprosate is just not yet for sale in the United States. While it continues to be widely studied in Europe the actual chemical belief that it works remains unknown. It is belief that it interferes with receptors inside the brain which process glutamate, which in effect alters the way ones body reacts to alcohol intake. Several of the European studies show a lot of promise with Acamprosate for the reason that some of the patients had a nearly double success rate for staying sober.